TABLE 4.
Age and sex-adjusted measures of cardiovascular risk factors according to categories of serum TSH concentration
|
Serum TSH concentration, mIU/L
|
P | |||||
|---|---|---|---|---|---|---|
| <0.27 | 0.27–1.57 | 1.58–2.88 | 2.89–4.19 | ≥4.2 | ||
| Body mass index, kg/m2 | 22.85±3.71 | 22.89±3.67 | 22.01±3.56 | 25.13±3.11 | 25.28±3.72 | 0.026 |
| Waist-to-hip ratio | 0.82±0.53 | 0.84±0.36 | 0.86±0.22 | 0.93±0.49 | 0.98±0.38 | <0.001 |
| Systolic blood pressure, mmHg | 137.21±16.08 | 127.27±21.32 | 130.33±19.27 | 131.69±20.97 | 137.45±21.03 | 0.367 |
| Diastolic blood pressure, mmHg | 80.33±8.79 | 79.91±12.56 | 79.12±12.06 | 78.84±11.38 | 80.17±10.45 | 0.174 |
| Fasting plasma glucose, mmol/L | 5.12±1.36 | 5.17±1.17 | 5.34±1.28 | 5.79±1.58 | 6.12±1.81 | 0.001 |
| Total cholesterol, mmol/L | 4. 63±1.33 | 4.87±1.13 | 4.96±1.25 | 4.99±1.23 | 5.35±1.64 | 0.013 |
| Triglycerides, mmol/L | 1.32±0.67 | 1.39±0.84 | 1.76±1.63 | 1.71±1.85 | 1.96±1.76 | 0.003 |
| LDL cholesterol, mmol/L | 3.03±0.85 | 2.97±0.71 | 2.88±0.84 | 2.91±0.73 | 3.18±0.91 | 0.124 |
| HDL cholesterol, mmol/L | 1.15±0.31 | 1.31±0.33 | 1.39±0.38 | 1.22±0.33 | 1.39±0.28 | 0.145 |
| Uric acid, μmol/L | 297.97±107.94 | 313.97±90.85 | 321.15±101.73 | 341. 62±70.90 | 371.63±109.47 | 0.174 |
| Smoking status, n | ||||||
| Nonsmokers | 17 | 121 | 159 | 72 | 60 | <0.001 |
| 1–339 cigarettes/year | 8 | 53 | 26 | 39 | 21 | 0.0008 |
| 440–1099 cigarettes/year | 2 | 37 | 21 | 26 | 16 | 0.0009 |
| >1100 cigarettes/year | 1 | 4 | 7 | 3 | 2 | 0.2222 |
Data presented as mean ± SD unless otherwise indicated. Groups were compared using a one-way ANOVA or χ2 test. P<0.05 was considered to be statistically significant. HDL High-density lipoprotein; LDL Low-density lipoprotein; TSH Thyroid stimulating hormone