Characterization of PCEC hydrogel. (A) Rheologic analysis of PCEC-micelles-PCEC-hydrogel dual-drug delivery system as a function of temperature. (B) Morphology of blank hydrogel (20 wt%) at 4°C and 37°C. (C) Scanning electron micrograph of PCEC hydrogel. (D) Cytotoxicity of the PCEC was determined by MTT assay.
Abbreviations: PCEC, poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone); MTT, 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; HEK, human embryonic kidney.