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Non-traditional phage antimicrobials. Phage can be engineered to express enzymes that disperse biofilms (blue) or as adjuvants that disrupt bacterial cellular regulatory networks and sensitize cells for further antibiotic treatment. Alternatively, phage lysin can be applied extracellularly to degrade cell walls. PlyC (PBD 4F88) is used to depict phage lysins, visualized with PyMOL.
