Table 2.
Summary of cervicovaginal histopathology in the 331 female rhesus macaques, of which 215 (65.0%) were SIV positive.
| Cervicovaginal histopathology | Total/% | # SIV+ | # With gross lesions/total | Selected representative cases |
|---|---|---|---|---|
| Increased lymphoid aggregates | 89/27% | 68 | 2/89 | Case 13 |
| Suppurative cervicitis and/or vaginitis | 38/12% | 24 | 14/38 | Cases 5, 6 |
| Dilated/cystic mucosal glands | 12/4% | 5 | 6/12 | |
| Metaplasia, hyperplasia, or dysplasia | 7/2% | 2 | 1/7 | Case 1 |
| Vascular abnormalities | 6/2% | 4 | 0/6 | |
| Vaginal/cervical polyp | 3/0.9% | 1 | 3/3 | Cases 2-4 |
| Leiomyoma | 2/0.6% | 0 | 2/2 | |
| Carcinoma | 1 | 1 | 1/1 | Case 7 |
| Serosal granulosa cell tumor | 1 | 0 | 1/1 | |
| Serosal endometriosis | 1 | 0 | 1/1 | |
| Myonecrosis and regeneration | 1 | 1 | 0/1 | |
| Pericervical abscess | 1 | 1 | 1/1 | |
| Erosive vaginitis | 1 | 1 | 0/1 | |
| Vaginal cryptosporidiosis | 1 | 1 | 0/1 | |
| Vaginal foreign body | 1 | 1 | 1/1 | |
| No significant findings | 165/50% | 105 | 0/165 | Cases 9-2 |