Table 3.
Summary of cases examined by immunohistochemical staining for immune cell subsets and papillomavirus induced lesions.
| Case # | Description | Age (years) | Species | Source | SIV | Ki-67 | E6 |
|---|---|---|---|---|---|---|---|
| 1 | SQMP and dysplasia | 25.0 | Mm | OC | − | +++ | + |
| 2 | Polyp | 14.0 | Mm | NEPRC | − | + | − |
| 3 | Cervicitis with polyp | 7.6 | Mm | NEPRC | SHIV+ | + | − |
| 4 | Cervicitis with dysplastic polyp | 23.3 | Mm | NEPRC | − | +++ | + |
| 5 | Suppurative cervicitis/vaginitis with SQMP | 3.9 | Mm | NEPRC | − | + | − |
| 6 | Suppurative cervicitis/vaginitis with SQMP | 15.1 | Mm | NEPRC | − | + | − |
| 7 | Anaplastic carcinoma | 12.7 | Mm | NEPRC | SIV+ | ++ | + |
| 8 | Papillary carcinoma | 14.9 | Sgo | NEPRC | − | + | + |
| 9 | WNL | ND | Mm | OC | − | − | − |
| 10 | WNL | 2.8 | Mm | NEPRC | − | − | − |
| 11 | WNL | 19.4 | Mm | OC | − | − | − |
| 12 | WNL | 6.6 | Mm | OC | − | − | − |
| 13 | Lymphoid aggregates, WNL | 11.6 | Mm | NEPRC | − | − | − |
Note. SQMP = squamous metaplasia; WNL = within normal limits; NEPRC = New England Primate Research Center; OC = other colony; Mm = Macaca mulatta; Sgo = Saguinus oedipus; SIV = Simian Immunodeficiency Virus; SHIV = Simian–human Immunodeficiency Virus; ND = not determined.
The amount of epithelial Ki-67 staining above the normal basal epithelial layers and the presence of papillomavirus E6 protein within the cervicovaginal epithelium is indicated.