Table 2. Dual-luciferase reporter gene assay.
n | ±s | |
miR-196b mimics+BCR-ABL1-3′-UTR | 3 | 532.793±111.245* |
miR-196b mimicscontrol+BCR-ABL1-3′-UTR | 3 | 1497.843±204.271 |
miR-196b mimics+BCR-ABL1-3′-UTR -mutant | 3 | 1523.627±109.590 |
lipo2000+BCR-ABL1-3′-UTR | 3 | 1488.233±94.823 |
lipo2000+BCR-ABL1-3′-UTR -mutant | 3 | 1473.147±158.225 |
F | 45.234 | (welch) |
P | <0.001 | |
miR-196b mimics+HOXA9-3′-UTR | 3 | 507.629±32.345# |
miR-196b mimics contro+HOXA9-3′-UTR | 3 | 1160.171±60.471 |
miR-196b mimics+ HOXA9-3′-UTR -mutant | 3 | 1080.374±121.249 |
lipo2000+ HOXA9-3′-UTR | 3 | 1197.352±162.872 |
lipo2000+HOXA9-3′-UTR-mutant | 3 | 1107.123±30.490 |
F | 168.622 | (welch) |
P | <0.001 |
vs. miR-196b mimics control+BCR-ABL1-3′-UTR, P = 0.006; * vs. miR-196b mimics+ BCR-ABL1-3′-UTR -mutant, P<0.001; * vs. lipo2000+ BCR-ABL1-3′-UTR, P<0.001; * vs. lipo2000+BCR-ABL1-3′-UTR -mutant, P = 0.001 (missing case, pairwise comparisons). # vs. miR-196b mimics contro+HOXA9-3′-UTR, P<0.001; # vs. miR-196b mimics+ HOXA9-3′-UTR -mutant, P = 0.016; # vs. lipo2000+ HOXA9-3′-UTR, P = 0.027; # vs. lipo2000+HOXA9-3′-UTR -mutant, P<0.001 (missing case, pairwise comparisons).