Table 5. Comparison of anatomical and functional characteristics of the TG and Non-TG mice.
Non-TG (n = 8) | TG (n = 7) | |
Body weight, g | 36.8±1.2 | 37.5±1.2 |
Systolic blood pressure, mmHg | 93±2 | 97±2 |
Heart rate, bpm | 633±22 | 625±13 |
LV weight/body weight, mg/g | 3.40±0.17 | 2.95±0.11 |
Atrial weight/body weight, mg/g | 0.25±0.01 | 0.39±0.05* |
Lung weight/body weight, mg/g | 4.12±0.25 | 4.27±0.13 |
Echocardiography | ||
LV end-diastolic dimension, mm | 3.76±0.10 | 3.84±0.11 |
PWd, mm | 0.98±0.03 | 0.95±0.04 |
Fractional shortening, % | 41±2 | 43±1 |
Data are mean ± SEM. LV indicates left ventricular; and PWd, LV posterior wall thickness at end-diastole.
P<0.05 vs. Non-TG mice.