Figure 1.

M2e-specific antibody titers induced by M2e-MAP vaccine. Mice were vaccinated with M2e-MAP plus Freund adjuvant (s. c.). Mice receiving Freund were used as negative controls. Sera were collected at 1, 2, 3, 4 weeks post first immunization. The titers were expressed as the highest serum dilution which is greater than twice the average absorbance value at OD450 nm of pre-vaccination sera. The data are expressed as geometric mean titer (GMT) ± standard deviation (SD) of 10 mice per group. The lower limit detection (1:20) is indicated by a dotted line. Experiments were repeated three times.