Table 3.

Unit operations for the synthesis of [¹⁸F]FDG

Unit operation		Description
1	INITIALIZE	Initialize hardware
2	TRAPF18	Trap [18F]fluoride for 120 s using 3 psi inert gas
3	ELUTEF18	Flow eluent through elute path for 120 s using 3 psi inert gas
4	EVAPORATE	Evaporate reactor 1 at 110°C for 300 s using 15 psi inert gas
5	ELUTEF18	Flow MeCN-1 through elute path for 90 s using 3 psi inert gas
6	EVAPORATE	Evaporate reactor 1 at 110°C for 120 s using 10 psi inert gas
7	ADD	Add MeCN-2 to reactor 1
8	EVAPORATE	Evaporate reactor 1 at 110°C for 120 s using 10 psi inert gas and cool to 30°C
9	ADD	Add mannose triflate to reactor 1
10	REACT	React reactor 1 at 130°C for 300 s and cool to 35°C with an additional 120s cooling delay
11	EVAPORATE	Evaporate reactor 1 at 110°C for 120 s using 10 psi inert gas
12	ADD	Add HCl to reactor 1
13	REACT	React reactor 1 at 130°C for 300 s and cool to 35°C with an additional 120-s cooling delay
14	TRANSFER	Transfer the contents of reactor 1 through the purification cartridge to the collection vial. Push with 10 psi inert gas for 30 s
15	ADD	Add Water-1 to reactor 1
16	TRANSFER	Transfer the contents of reactor 1 through the purification cartridge to the collection vial. Push with 10 psi inert gas for 30 s
17	ADD	Add Water-2 to reactor 1
18	TRANSFER	Transfer the contents of reactor 1 through the purification cartridge to the collection vial. Push with 10 psi inert gas for 45 s