Table 1.
Demographic, listing, and peri-transplant characteristics in patients with pre-OLT renal dysfunction that are associated with recovery of renal function post-OLT
| Recovery of renal function (n=863) | Non-recovery (n=857) | p | OR (95% CI) | |
|---|---|---|---|---|
|
Demographic characteristics |
|
|
|
|
| Age |
50.3 ± 10.2 |
50.0 ± 10.5 |
0.3 |
|
| Sex (male) |
544 (63%) |
581 (67%) |
0.043 |
0.81 (0.66-0.98) |
| Race (Caucasian) |
599 (70%) |
620 (72%) |
0.21 |
0.88 (0.70-1.07) |
|
Listing characteristics |
|
|
|
|
| ICU admission |
207 (24%) |
255 (29%) |
0.007 |
0.74 (0.60-0.92) |
| Mechanical ventilation |
108 (13%) |
172 (20%) |
0.00001 |
0.57 (0.43-0.74) |
| Encephalopathy |
510 (59%) |
541 (60%) |
0.35 |
1.08 (0.9-1.3) |
| Ascites |
593 (72%) |
598 (63%) |
0.60 |
0.95 (0.75-1.16) |
| TIPS |
57 (6.6%) |
63 (7%) |
0.63 |
0.92 (0.65-1.30) |
| PVT |
17 (1.9%) |
30 (3.5%) |
0.052 |
0.55 (0.32-0.93) |
| Dialysis (at listing)* |
248 (28%) |
303 (32%) |
0.003 |
0.63 (0.50-0.76) |
| BMI (kg/m2) |
27.6 ± 5.5 |
28.4 ± 6.1 |
0.02 |
|
|
Peri-transplant characteristics |
|
|
|
|
| Wait time from listing (days) |
178 ± 297 |
145 ± 266 |
0.00001 |
|
| ICU admission |
441 (51%) |
417 (49%) |
0.76 |
1.03 (0.85-1.20 |
| Mechanical ventilation |
206 (24%) |
249 (29%) |
0.015 |
0.76 (0.62-0.95) |
| Encephalopathy |
343 40%) |
344 (41%) |
0.86 |
0.98 (0.81-1.20) |
| Ascites |
580 (67%) |
547 (64%) |
0.14 |
1.20 (0.95-1.40) |
| TIPS |
75 (8.6%) |
79 (9.2%) |
0.70 |
0.93 (0.67-1.30) |
| PVT |
22 (2.5%) |
39 (4.5%) |
0.025 |
0.55 (0.32-0.99) |
| Dialysis (at transplant)* |
421 (49%) |
471 (55%) |
0.01 |
0.70 (0.57-0.85) |
| Dialysis (at both listing and transplant) |
169 (19%) |
204 (23%) |
0.03 |
0.78 (0.62-0.99) |
| BMI (kg/m2) | 27.0 ± 6.4 | 28.0 ± 6.3 | 0.019 |
Abbreviations: BMI body mass index, CI confidence interval, ICU intensive care unit, OLT orthotopic liver transplant, OR odds ratio, PVT portal vein thrombosis, TIPS transjugular intrahepatic porto-systemic shunt.
* The number of patients on dialysis at listing (n = 551) includes those on dialysis only at listing (n = 178) as well as those on dialysis at both listing and transplant (n = 373). Similarly, the number of patients on dialysis at transplant (n = 892) includes those on dialysis only at listing (n = 519) as well as those on dialysis at both listing and transplant (n = 373).