Table 4.
Laboratory values in patients with pre-OLT renal dysfunction associated with recovery of renal function post-OLT
| Recovery of renal function(n = 863) | Non-recovery (n = 857) | p | |
|---|---|---|---|
| SCr at time of registration (mg/dL)* |
2.4 ± 2.0 |
2.9 ± 2.6 |
0.00001 |
| SCr at time of registration (mg/dL) |
|
|
|
| (adjusted for dialysis, SCr = 4 mg/dL)* |
2.5 ± 1.6 |
2.4 ± 1.7 |
0.23 |
| SCr at time of registration (mg/dL) |
|
|
|
| (adjusted for dialysis, SCr = 5 mg/dL)* |
2.8 ± 2.0 |
2.78 ± 2.0 |
0.30 |
| SCr at time of transplant |
3.6 ± 2.0 |
4.0 ± 2.3 |
0.00001 |
| SCr at time of transplant (mg/dL) |
|
|
|
| (adjusted for dialysis, SCr = 4 mg/dL) |
3.84 ± 1.5 |
3.8 ± 1.4 |
0.52 |
| SCr at time of transplant (mg/dL) |
|
|
|
| (adjusted for dialysis, SCr = 5 mg/dL) |
4.3 ± 1.6 |
4.3 ± 1.6 |
0.80 |
| eGFR at time of registration (cc/min) |
57 ± 41 |
50 ± 42 |
0.00001 |
| eGFR at time of registration (cc/min) |
|
|
|
| (adjusted for dialysis, SCr = 4 mg/dL) |
51 ± 42 |
53 ± 44 |
0.33 |
| eGFR at time of registration (cc/min) |
|
|
|
| (adjusted for dialysis SCr = 5 mg/dL) |
51 ± 43 |
53 ± 46 |
0.33 |
| eGFR at time of transplant (cc/min) |
28 ± 21 |
22 ± 14 |
0.00001 |
| eGFR at time of transplant (cc/min) |
|
|
|
| (adjusted for dialysis, SCr = 4 mg/dL) |
20 ± 14 |
21 ± 12 |
0.30 |
| eGFR at time of transplant (cc/min) |
|
|
|
| (adjusted for dialysis, SCr = 5 mg) |
19 ± 14 |
19 ± 12 |
0.49 |
| Serum ALT at time of transplant (units/L) |
257 ± 888 |
489 ± 1379 |
0.007 |
| INR at time of transplant |
2.1 ± 1.5 |
2.2 ± 2.8 |
0.80 |
| Total bilirubin at time of transplant (mg/dL) |
14.0 ± 14.4 |
16.0 ± 16.0 |
0.38 |
| Serum albumin at time of transplant (g/dL) | 2.78 ± 0.76 | 2.82 ± 0.77 | 0.18 |
* For patients receiving RRT, several values of SCr were used, an unadjusted and two adjusted values. The unadjusted SCr was the value entered into the UNOS database. Given uncertainty whether the entered SCr was obtained pre- or post-dialysis, analysis was repeated using a single adjusted value for SCr of either 4.0 or 5.0 mg/dL.
Abbreviations: ALT alanine transaminase, eGFR estimated glomerular filtration rate, INR international normalized ratio, OLT orthotopic liver transplantation, SCr serum creatinine.