Table 5.
Pathologic features of patients with papillary thyroid cancer (PTC) by group in patients with and without Hashimoto’s thyroiditis (HT)
| Characteristics |
Group I |
Group II |
χ2 | P-value |
|---|---|---|---|---|
|
(with HT) |
(without HT) |
|||
| n = 187 | n = 817 | |||
| Pathological TNM staging |
|
|
0.540 |
0.910 |
| I |
160 (85.6) |
687 (84.1) |
|
|
| II |
4 (2.1) |
25 (3.1) |
|
|
| III |
15 (8.0) |
70 (8.6) |
|
|
| IV |
8 (4.3) |
35 (4.3) |
|
|
| Tumor size |
|
|
2.975 |
0.209 |
| ≤1 cm |
126 (67.4) |
496 (60.7) |
|
|
| 1 to 4 cm |
59 (31.6) |
304 (37.2) |
|
|
| >4 cm |
2 (1.1) |
17 (2.1) |
|
|
| Frequency of occult PTC |
|
|
2.872 |
0.090 |
| Absent |
61 (32.6) |
321(39.3) |
|
|
| Present |
126 (67.4) |
496 (60.7) |
|
|
| Lymph nodes metastases |
|
|
0.227 |
0.634 |
| Absent |
129 (69.0) |
578 (70.7) |
|
|
| Present |
58 (31.0) |
239 (29.3) |
|
|
| Distribution of positive lymph nodes |
|
|
4.703 |
0.427 |
| Level VI |
49 (58.3) |
217 (54.5) |
|
|
| Level II |
9 (10.7) |
33 (8.3) |
|
|
| Level III |
9 (10.7) |
48 (12.1) |
|
|
| Level IV |
10 (11.9) |
47 (11.8) |
|
|
| Level V |
6 (7.1) |
52 (13.1) |
|
|
| Level I |
1 (1.2) |
1 (0.3) |
|
|
| Extrathyroidal invasion |
|
|
0.885 |
0.347 |
| Absent |
184 (98.4) |
794 (97.2) |
|
|
| Present |
3 (1.6) |
23 (2.8) |
|
|
| Capsular infiltration |
|
|
0.891 |
0.345 |
| Absent |
159 (85.0) |
671 (82.1) |
|
|
| Present |
28 (15.0) |
146 (17.9) |
|
|
| Vascular invasion |
|
|
0.429 |
0.512 |
| Absent |
186 (99.5) |
815 (99.8) |
|
|
| Present |
1 (0.5) |
2 (0.2) |
|
|
| Distant metastases | 0 | 0 |
Results for Groups I and II are presented as number (%) of patients. *Statistically significant (P <0.05).