Table 1.
Clinical presentations of two types of atypical HFMD
| A typical HFMD (N=101) | Large vesicles (N=50) | Small rashes (N=51) | P value* | |
|---|---|---|---|---|
|
Demographics | ||||
| Age (year) |
3.3 (± 3.8) |
4.0 (± 3.7) |
2.7 (± 1.8) |
0.12 |
| Male |
65 (64%) |
35 (70%) |
30 (59%) |
0.004 |
| Female |
36 (36%) |
15 (30%) |
21 (41%) |
|
|
Etiology | ||||
| CVA6 |
81 (80%) |
45 (90%) |
36 (70%) |
0.01 |
|
Sites | ||||
| Limbs |
98 (97%) |
49 (98%) |
49 (96%) |
1.00 |
| Arm/Leg/Thigh |
71 (70%) |
35 (70%) |
36 (70%) |
1.00 |
| Trunk |
29 (29%) |
21(42%) |
8 (16%) |
0.004 |
| Buttocks |
31 (31%) |
17 (34%) |
14 (27%) |
0.52 |
| Face |
40 (41%) |
22 (44%) |
18 (35%) |
0.42 |
| Ear lobes |
11 (11%) |
6 (12%) |
5 (10%) |
0.76 |
| Perioral area |
26 (26%) |
16 (32%) |
10 (20%) |
0.18 |
|
Symptoms | ||||
| Fever |
80 (80%) |
40 (80%) |
39 (76%) |
0.81 |
| Sore throat |
59 (58%) |
33 (66%) |
26 (51%) |
0.16 |
| Cough/rhinorrhea |
27 (27%) |
14 (28%) |
13 (25%) |
0.83 |
| Vomit/diarrhea |
17 (17%) |
6 (12%) |
11 (22%) |
0.29 |
| Skin lesions | ||||
| Itchiness |
32 (32%) |
22 (44%) |
10 (20%) |
0.01 |
| Desquamation |
1 (1%) |
1 (2%) |
0 (0%) |
0.50 |
| Pigmentation |
6 (9%) |
5 (10%) |
1 (2%) |
0.11 |
| Prickle |
2 (2%) |
2 (4%) |
0 (0%) |
0.24 |
| Myoclonic jerks |
14 (14%) |
5 (10%) |
9 (18%) |
0.39 |
| Myalgia | 2 (2%) | 2 (4%) | 0 (0%) | 0.24 |
* P value represents the comparison of total numbers between male and female.