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. 2013 Jul 12;6:52. doi: 10.1186/1756-8722-6-52

Table 1.

Summary of clinical data of patients used in the present study

Inv. Assigned code Gender Diagnosis Age at diagnosis (yrs) Survival Survival time (yrs) (WBC) [x103/ul] TEL/AML1 BCR/ABL MLL Karyotype RISK MRD Clinical outcome
1
 X1
 F
 common
 2.43
 1
 2.93
 1200.00
 -
 -
 -
  
 L
 -
 CR
2
 X2
 M
 common
 4.07
 1
 2.75
 3570.00
 -
 -
 -
 46XY
 L
 -
 CR
3
 X3
 F
 common
 4.10
 1
 3.15
 5700.00
 -
 +
 -
 46ΧΧ, one clone with chromosome 7 t(1;19)
 H
 -
 CR
4
 X4
 M
 common
 2.75
 2
 1.12
 48000.00
 +
 -
 -
 46ΧΥ, ΤδΤ-
 H
 -
 CR
5
 X5
 M
 common
 7.77
 1
 3.01
 18800.00
 -
 -
 -
 46XY
 H
 -
 CR
6
 X6
 M
 pro-B
 2.35
 1
 6.47
 4400.00
 -
 -
 -
 trisomy 4, 6,18,22. X trisome in 5 metaphases
 H
 -
 CR
7
 X7
 M
 common
 5.13
 1
 4.36
 13800.00
 -
 -
 -
  
 L
 -
 CR
8
 X8
 M
 common
 2.19
 2
 0.45
 7100.00
 -
 -
 -
  
 H
 -
 CR
9
 X9
 M
 common
 5.28
 1
 0.63
 8050.00
 -
 -
 -
  
 L
 -
 CR
10
 X10
 M
 common
 1.83
 2
 3.84
 58600.00
 -
 -
 -
 50ΧΥ, , +Χ, t(5;7)(p11;q11), +14,add(14)(p11.1)+21,+21[13]/46,XY[1], hyperdiploidy: trisomy 14, 21, 22, Χ, total chromosomes 50, in one metaphase, 51 chromosomes with tetrasome 21
 H
 -
 Relapse
11
 X11
 F
 pre-B
 4.08
 1
 2.54
 1220.00
 -
 -
 -
  
 L
 -
 CR
12
 X12
 F
 common
 6.72
 1
 4.05
 67980.00
 -
 -
 -
 46ΧΧ
 H
 -
 CR
13
 X13
 F
 common
 2.94
 1
 3.79
  
 +
 -
 -
 46ΧΧ
 L
 -
 CR
14
 X14
 F
 common
 1.01
 1
 3.32
 42000.00
 -
 -
 -
  
 H
 -
 CR
15
 X15
 F
 common
 5.80
 1
 4.99
 4370.00
 -
 -
 -
 56XX, trisomy 4,6,8,10,11,14,15, tetrasomy 21,
 H
 -
 CR
16
 X16
 F
 common
 6.05
 2
 1.82
 137000.00
 -
 +
 -
 46XX, t(9;22)(q34;q1) mutual translocation between chromosomes 9 +1, chromosome 22, BCR/ABL: 92%
 H
 -
 CR
17
 X17
 M
 pre-B
 14.85
 2
 1.54
 92960.00
 -
 +
 -
 45ΧΥ, BCR/ABL 97,2%+ MLL- TEL/AML1-
 H
 -
 CR
18
 X18
 M
 common
 1.93
 1
 4.76
 5600.00
 -
 -
 -
 59XXY, hyperdiploidy +4,+6,+8,+29,+10,+11,+15,+17,+20,+21*2,
 H
 -
 CR
19
 X19
 M
 common
 2.02
 1
 5.01
 1380.00
 -
 -
 -
 46XY
 L
 -
 CR
20
 X20
 F
 common
 2.23
 1
 2.11
 9670.00
 -
 -
 -
  
 L
 -
 CR
21
 X21
 F
 common
 2.86
 1
 4.50
 14700.00
 -
 -
 -
  
 L
 -
 CR
22
 X22
 F
 common
 3.30
 1
 2.67
 30820.00
 +
 -
 -
  
 L
 -
 CR
23
 X23
 M
 common
  
 1
 2.56
  
 -
 -
 -
  
 H
 -
 CR
24
 X24
 M
 common
 14.04
 2
 3.11
 670.00
 -
 -
 -
  
 H
 -
 Relapse
25
 X25
 F
 common
 4.41
 1
 5.00
 10440.00
 -
 -
 -
  
 L
 -
 CR
26
 X26
 F
 common
 13.72
 1
 3.09
 4000.00
 +
 -
 -
 46XX, t(1;19)(q23p13)83,7%
 H
 -
 CR
27
 X27
 F
 common
 14.41
 1
 4.56
 2220.00
 -
 -
 -
 55XX+X, +4,+8, +14, +17, +18, +21 [8]/46XX[2]
 H
 -
 CR
28
 X28
 M
 common
 2.92
 1
 2.09
 8100.00
 -
 -
 -
  
 L
 -
 CR
29
 X29
 F
 common
 5.25
 1
 4.37
 6520.00
 +
 -
 -
 46ΧΧ
 L
 -
 CR
30
 X30
 F
 L3
 5.49
 1
 4.03
 3700.00
 -
 -
 -
 49XX, xx,+4, +21,/46XX
 H
 -
 CR
31
 X31
 F
 common
 -0.70
 1
 3.86
 74800.00
 -
 -
 +
 46XX
 H
 -
 CR
32
 X32
 F
 common
 4.97
 2
 1.42
 10610.00
 -
 -
 -
 46XX
 L
 -
 CR
33
 X33
 F
 common
 6.97
 1
 4.11
 4000.00
 -
 -
 -
  
 H
 -
 CR
34
 X34
 M
 common
 7.86
 1
 4.02
 10270.00
 +
 -
 -
 46 XY
 L
 -
 CR
35
 X35
 F
 pro-B
 3.23
 1
 3.46
 22900.00
 +
 -
 -
 46xx, , TEL/AML1: 97.3%, E2A'+
 L
 -
 CR
36
 X36
 M
 common
 2.87
 1
 4.15
 6670.00
 +
 -
 -
  
 L
 -
 CR
37
 X37
 M
 common
 14.21
 1
 2.75
 21000.00
 -
 +
 -
 46XY, 1(q)(q0) del13 del19 t(1;19)-del13, BCR/ABL 90,7%+ TCF3E2A/PBX1 (1;19) 95%+
 H
 -
 CR
38
 X38
 M
 common
 7.47
 1
 3.50
 55050.00
 -
 -
 -
  
 H
 -
 CR
39
 X39
 M
 common
 13.61
 1
 7.75
  
 -
 -
 -
  
 H
 -
 CR
40
 X40
 F
 common
 3.13
 1
 4.08
 17000.00
 -
 -
 -
  
 L
 -
 CR
41
 X41
 M
 common
 1.75
 1
 2.93
 4400.00
 +
 -
 -
 Tcf3 (E2A)-, AML1: 4 copies (+)50%
 L
 +
 CR
42
 X42
 F
 pro-B
 9.31
 1
 3.04
 3000.00
 +
 -
 -
 TEL/AML(78,7%)
 H
 -
 CR
43
 X43
 M
 common
 1.01
 1
 3.57
 8800.00
 -
 -
 +
 48XY+X mutual translocation 11 or 19. 1 extra Χ, translocation between 2 Η 9, 1 extra chromosome 6, MLL 92%
 H
 -
 CR
44
 X44
 F
 common
 0.16
 1
 3.84
 84000.00
 -
 -
 +
 46XX, MLL:95.8%,
 H
 +
 CR
45 X45 F common 3.22 2 2.52 33280.00 + - - 46ΧΧ/49ΧΧ,+Χ, +10 +21 ΤΕL/AML96,6% H - CR

(Legends: Inv: Invoice, Assigned Code: Internal patient laboratory code,Survival: 1: Alive, 2: Deceased, MRD: Minimal Residual Disease) MRD detection at the end of induction (28th day), Risk: L:Low, H:High.