Table 3.

Correlations between random effects of pharmacokinetic parameters and covariates (from the model without outliers)

	CL	V d	Age	WT	ALT	AST	BIL	ALB	CRCL
CL	100	15 (−36 to 66)	−7.7 (−22 to 6.3)	31 (13 to 48)	−8.5 (−22 to 5.4)	−12 (−25 to −0.15)	−11 (−33 to 10)	−8.5 (−26 to 9.4)	8.2 (−13 to 29)
V d		100	9.5 (−44 to 63)	13 (−20 to 47)	−5.1 (−27 to 17)	−0.13 (−19 to 19)	12 (−18 to 41)	−13 (−31 to 5.7)	−8.1 (−39 to 23)

Data are percentage correlation of random effects (95 % CI). Correlations between covariates are not shown. The correlations where the standard errors were less than 100 % of the correlation value are bolded

ALB albumin, ALT alanine aminotransferase, AST aspartate aminotransferase, BIL bilirubin, CL clearance, CRCL creatinine clearance, V _d volume of distribution, WT body weight