FIG. 7.
Changes in renal expression of Nrf2 gene. Renal expression of Nrf2/ARE gene in biopsies collected before (pre) and 45 min after (post) reperfusion during LD and DD kidney transplantation. Y-axis shows the relative change in gene expression as calculated by log(1/2ddCt), where the dCt is the Ct of studied gene minus the Ct of GAPDH, and ddCt is dCt of postbiopsy minus dCt of prebiopsy. A positive number indicates an increase in expression after reperfusion, whereas a negative number indicates a downregulation after reperfusion. Expression of the transcription factor Nrf2 gene NFE2L2 was significantly upregulated after reperfusion in both LD (p=0.03) and DD (p=0.04) kidney grafts.