Table 1.
Properties of dwell time distributions
| Apparent open periods | ||||
|---|---|---|---|---|
| Gly (μm) | τ1 (ms) | τ2 (ms) | τ3 (ms) | |
| (n) | (area (%)) | (area (%)) | (area (%)) | Mean open time (ms) |
| 50 | 0.15 ± 0.05 | 0.9 ± 0.2 | 4.6 ± 0.6 | 2.2 ± 0.5 |
| (4) | (20 ± 10) | (44 ± 4) | (40 ± 10) | |
| 200 | 0.09± 0.03 | 1.5 ± 0.1 | 5.3 ± 0.8 | 3.9 ± 0.6 |
| (4) | (5 ± 1) | (33 ± 4) | (61 ± 5) | |
| 300 | 0.07± 0.04 | 1.7 ± 0.3 | 5.7 ± 0.3 | 5.1 ± 0.04 |
| (3) | (3 ± 1) | (16 ± 3) | (81 ± 3) | |
| 1000 | 0.11± 0.09 | 3.8 ± 2 | 12 ± 2 | 8.6 ± 1.1 |
| (4) | (8 ± 4) | (30 ± 10) | (60 ± 20) | |
| 10,000 | 0.07 ± 0.04 | 5.6 ± 3 | 30 ± 10 | 23.9 ± 8.9 |
| (2) | (2.2 ± 0.4) | (17 ± 9) | (81 ± 9) | |
| Apparent shut times | ||||
|---|---|---|---|---|
| Gly (μm) | τ1 (ms) | τ2 (ms) | τ3 (ms) | τ4 (ms) |
| (n) | (area (%)) | (area (%)) | (area (%)) | (area (%)) |
| 50 | 0.04 ± 0.02 | 0.33 ± 0.06 | 2.9 ± 0.8 | 1700 ± 600 |
| (4) | (49 ± 7) | (28 ± 4) | (5 ± 1) | (17 ± 4) |
| 200 | 0.03 ± 0.01 | 0.27± 0.07 | 30 ± 20 | 200 ± 60 |
| (4) | (62 ± 1) | (26 ± 2) | (6 ± 1) | (5 ± 1) |
| 300 | 0.009 ± 0.001 | 0.3 ± 0.2 | 0.50 ± 0.05 | 38 ± 6 |
| (3) | (88 ± 2) | (8 ± 1) | (3 ± 1) | (0.9 ± 0.2) |
| 1000 | 0.01 ± 0.004 | 0.05 ± 0.02 | 0.3 ± 0.1 | 1.9 ± 0.5 |
| (4) | (61 ± 7) | (30 ± 6) | (9 ± 3) | (1 ± 0.3) |
| 10,000 | 0.010 ± 0.001 | 0.03 ± 0.02 | 0.4 ± 0.2 | 1.2 ± 0.7 |
| (2) | (70 ± 30) | (30 ± 30) | (2 ± 1) | (0.2 ± 0.1) |
Distributions were fitted with mixtures of exponential probability density functions. n, the number of patches for each concentration (indicated in parentheses in the first column). The time constant of each component and its relative area (in parentheses) are given as mean ± SD of the mean.