Figure 6. Different growth behaviors of primary cells and cancer cells as evidenced by voxel-based parameters.

When comparing primary cell data (dark, diamond markers) to cancer cell data (light, square markers), it can be seen that while primary cells correlate well to growth capacity (as measured by doubling time), cancer cells do not. In this figure, both cond and meth are fit with a logistic curve, which was determined to be the best fitting curve based on F-test results. Parametric values from cancer cell populations lie further away from fitted curves and from primary cell populations.