Fig. 1.

LCMSMS chromatogram of a real sweat patch positive to ecgonine methyl ester (EME, 75.5 ng/patch), trans-3′-hydroxycotinine (OH-cotinine, 17.6 ng/patch), cotinine (181.0 ng/patch), morphine (10.1 ng/patch), 6-acetylmorphine (6AM, 4.8 ng/patch), benzoylecgonine (BE, 89.0 ng/patch), heroin (1.4 ng/patch), cocaine (705.0 ng/ patch), and buprenorphine (BUP, 1.6 ng/patch). Quantitation transition of these analytes in the first (a), second (b) and third (c) acquisition windows are included in separate panels