Table 2.
Limits of detection (LOD), limits of quantification (LOQ) and linearity results
Analyte | LOD (ng/patch) | LOQ (ng/patch) | Linearity (ng/patch) | Intercept±SD (n=4) | Slope±SD (n=4) | r2±SD (n=4) |
---|---|---|---|---|---|---|
EME | 2.5 | 5 | 5–1000 | −0.0013±0.0025 | 0.0112±0.0010 | 0.9972±0.0023 |
BE | 0.5 | 1 | 1–1000 | 0.0016±0.0008 | 0.0071±0.0004 | 0.9926±0.0013 |
Cocaine | 0.5 | 1 | 1–1000 | 0.0003±0.0001 | 0.0019±0.0001 | 0.9964±0.0013 |
Morphine | 0.75 | 1 | 1–1000 | 0.0058±0.0025 | 0.0381±0.0044 | 0.9936±0.0030 |
Codeine | 0.75 | 1 | 1–1000 | 0.0004±0.0013 | 0.0101±0.0003 | 0.9963±0.0032 |
6AM | 0.75 | 1 | 1–1000 | 0.0004±0.0018 | 0.0114±0.0006 | 0.9991±0.0004 |
6AC | 0.75 | 1 | 1–1000 | 0.0009±0.0007 | 0.0077±0.0004 | 0.9967±0.0002 |
Heroin | 0.5 | 1 | 1–1000 | 0.0010±0.0005 | 0.0104±0.0002 | 0.9978±0.0002 |
Cotinine | 0.75 | 1 | 1–1000 | 0.0067±0.0019 | 0.0115±0.0006 | 0.9962±0.0017 |
OH-Cotinine | 0.75 | 1 | 1–1000 | 0.0008±0.0007 | 0.0073±0.0002 | 0.9977±0.0012 |
Methadone | 0.5 | 1 | 1–1000 | 0.0001±0 | 0.0014±0.0001 | 0.9929±0.0008 |
EDDP | 0.5 | 1 | 1–1000 | 0.0015±0.0003 | 0.0088±0.0006 | 0.9928±0.0028 |
BUP | 0.5 | 1 | 1–1000 | 0.0001±0.0013 | 0.0182±0.0007 | 0.9980±0.0005 |
NBUP | 0.75 | 1 | 1–1000 | 0.0047±0.0024 | 0.0074±0.0003 | 0.9967±0.0019 |