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. Author manuscript; available in PMC: 2013 Jul 21.
Published in final edited form as: Am J Drug Alcohol Abuse. 2011 Jul 29;38(1):114–119. doi: 10.3109/00952990.2011.600398

FIGURE 1.

FIGURE 1

Plasma cortisol concentrations (μg/dL) before and after single placebo, 20, or 40 mg rimonabant doses in daily cannabis smokers. Ten cannabis smokers were administered Δ9-tetrahydrocannabinol (THC) 20 mg orally every 4–8 hours in escalating daily doses for 8 days to maintain and standardize cannabis tolerance (120 mg/day for 3 days prior to rimonabant). At 9:30 on the ninth day (arrow), subjects A, B, C, D, and E (dashed lines) received oral rimonabant 20 mg concurrently with the last dose of THC; subjects F, G, and H (gray lines) received oral rimonabant 40 mg concurrently with the last dose of THC. Subjects I and J (black lines) received placebo rimonabant.

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