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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Pediatr Infect Dis J. 2013 May;32(5):450–459. doi: 10.1097/INF.0b013e318287b408

Table 1.

Clinical features of pediatric epilepsy surgery with and without postoperative infections (n=100).

Variable Infected (n=15) Non Infected (n=85) p-value

Age Seizure Onset (years) 1.1±1.8 3.7±4.4 0.024

Age at Surgery (years) 4.9±3.9 8.8±6.0 0.019

Epilepsy Duration (years) 3.9±2.9 5.0±4.7 0.362

Female (n=46) 53% 45% 0.536

Left Resection (n=48) 33% 50% 0.217

History of Infantile Spasms (n=40) 67% 35% 0.022

Daily Seizures (n=77) 79% 75% 0.623

Repeat Craniotomy (n=15) 13% 15% 0.844

In Status Epilepticus (n=4) 7% 4% 0.568

Operation Type
 Hemispherectomy (n=43) 67% (n=10) 39% (n=33) 0.021
 Multilobar Resection (n=11) 20% (n=3) 9% (n=8)
 Lobar/Focal (n=46) 13% (n=2) 52% (n=44)

Etiology
 Cortical Dysplasia (n=45) 33% (n=5) 47% (n=40) 0.0027*
 Ischemia/Atrophy (n=12) 7% (n=1) 13% (n=11)
 Tuberous Sclerosis Complex (n=11) 20% (n=3) 9% (n=8)
 Tumor (n=10) 7% (n=1) 10% (n=9)
 Rasmussen (n=8) 0% (n=0) 9% (n=8)
 Hemimegalencephaly (n=5) 20% (n=3) 2% (n=2)
 Hippocampal Sclerosis (n=3) 0% (n=0) 4% (n=3)
 History of infection (n=2) 13% (n=2) 0% (n=0)
 Sturge-Weber (n=2) 0% (n=0) 2% (n=2)
 Non-Diagnostic (n=2) 0% (n=0) 2% (n=2)

Seizure Free Last Follow-Up (n=93) 71% 75% 0.797

Other Complication (n=6) 7% 6% 0.906

New CSF Shunts (n=10) 20% 8% 0.161

Duration of Hospital Stay (days) 17.9±10.2 8.5±5.5 P<0.0001*

Private Insurance (n=77) 87% 75% 0.335

Ethnic Category
 White (n=70) 73% 69% 0.929
 Hispanic/Latino (n=16) 13% 16%
 Asian (n=9) 13% 8%
 African-American (n=2) 0% 2%
 Middle-East (n=2) 0% 2%
 Mixed (n=1) 0% 1%

Underlined values indicate significant contribution to Chi-square.

*

indicates that both factors remain significant (p<0.01) in logistical regression analysis. Data presented as mean (±SD) or percentages. Repeat craniotomy consisted of 7 patients having second surgery for incomplete cerebral hemispherectomy disconnections, 4 cases of enlargement of prior focal resections, 3 cases of staged resections for tuberous sclerosis complex, and 1 case of staged resection for Rasmussen encephalitis. All prior operations were before accruement for this cohort.

Significant values (p<0.01) indicated in Bold type.