Table 1.
Variable | Infected (n=15) | Non Infected (n=85) | p-value |
---|---|---|---|
| |||
Age Seizure Onset (years) | 1.1±1.8 | 3.7±4.4 | 0.024 |
| |||
Age at Surgery (years) | 4.9±3.9 | 8.8±6.0 | 0.019 |
| |||
Epilepsy Duration (years) | 3.9±2.9 | 5.0±4.7 | 0.362 |
| |||
Female (n=46) | 53% | 45% | 0.536 |
| |||
Left Resection (n=48) | 33% | 50% | 0.217 |
| |||
History of Infantile Spasms (n=40) | 67% | 35% | 0.022 |
| |||
Daily Seizures (n=77) | 79% | 75% | 0.623 |
| |||
Repeat Craniotomy (n=15) | 13% | 15% | 0.844 |
| |||
In Status Epilepticus (n=4) | 7% | 4% | 0.568 |
| |||
Operation Type | |||
Hemispherectomy (n=43) | 67% (n=10) | 39% (n=33) | 0.021 |
Multilobar Resection (n=11) | 20% (n=3) | 9% (n=8) | |
Lobar/Focal (n=46) | 13% (n=2) | 52% (n=44) | |
| |||
Etiology | |||
Cortical Dysplasia (n=45) | 33% (n=5) | 47% (n=40) | 0.0027* |
Ischemia/Atrophy (n=12) | 7% (n=1) | 13% (n=11) | |
Tuberous Sclerosis Complex (n=11) | 20% (n=3) | 9% (n=8) | |
Tumor (n=10) | 7% (n=1) | 10% (n=9) | |
Rasmussen (n=8) | 0% (n=0) | 9% (n=8) | |
Hemimegalencephaly (n=5) | 20% (n=3) | 2% (n=2) | |
Hippocampal Sclerosis (n=3) | 0% (n=0) | 4% (n=3) | |
History of infection (n=2) | 13% (n=2) | 0% (n=0) | |
Sturge-Weber (n=2) | 0% (n=0) | 2% (n=2) | |
Non-Diagnostic (n=2) | 0% (n=0) | 2% (n=2) | |
| |||
Seizure Free Last Follow-Up (n=93) | 71% | 75% | 0.797 |
| |||
Other Complication (n=6) | 7% | 6% | 0.906 |
| |||
New CSF Shunts (n=10) | 20% | 8% | 0.161 |
| |||
Duration of Hospital Stay (days) | 17.9±10.2 | 8.5±5.5 | P<0.0001* |
| |||
Private Insurance (n=77) | 87% | 75% | 0.335 |
| |||
Ethnic Category | |||
White (n=70) | 73% | 69% | 0.929 |
Hispanic/Latino (n=16) | 13% | 16% | |
Asian (n=9) | 13% | 8% | |
African-American (n=2) | 0% | 2% | |
Middle-East (n=2) | 0% | 2% | |
Mixed (n=1) | 0% | 1% |
Underlined values indicate significant contribution to Chi-square.
indicates that both factors remain significant (p<0.01) in logistical regression analysis. Data presented as mean (±SD) or percentages. Repeat craniotomy consisted of 7 patients having second surgery for incomplete cerebral hemispherectomy disconnections, 4 cases of enlargement of prior focal resections, 3 cases of staged resections for tuberous sclerosis complex, and 1 case of staged resection for Rasmussen encephalitis. All prior operations were before accruement for this cohort.
Significant values (p<0.01) indicated in Bold type.