Table 2.
Surgeries, Organism, and Sites of Treated Infection in Pediatric Epilepsy Surgery Cases
| Surgery | Site | Organism | Age at Seizure Onset (y) | Age at Surg (y) | Etiology | POD when infection identified | Antibiotic, duration (days) | |
|---|---|---|---|---|---|---|---|---|
| 1 | Hemi | CSF | Pseudomonas aeruginosa | 0.8 | 9.3 | Cortical Dysplasia | 5 | Vancomycin, 3 Meropenem, 22 Ceftazidime, 3 Gentamicin,29 Piperacillin/tazobactam, 4 |
| 2 | Hemi | CSF | Enterobacter cloacae | 0.0 | 0.2 | Hemimeg. | 9 | Ceftriaxone, 7 Meropenem, 22 Gentamicin, 28 |
| 3 | Hemi | CSF and blood | Acinetobacter species in CSF, Candida albicans and Pseudomonas putida in blood | 5.8 | 7.8 | Hemimeg. | 6 CSF, 17-blood | Vancomycin, 6 Gentamicin, 7 Tobramycin, 8 Micafungin, 7 Ceftriaxone, 2 Meropenem, 21 Ciprofloxacin, 10 Fluconazole, 2 |
| 4 | Hemi | CSF | CONS | 0.8 | 3.5 | Cortical Dysplasia | 7 | Vancomycin, 16 Gentamicin, 2 Ceftriaxone, 16 Bacitracin, 6 |
| 5 | Hemi | Urine | Pseudomonas aeruginosa | 0.3 | 2.5 | Cortical Dysplasia | 6 | Ceftazidime, 4 |
| 6 | Hemi | Urine | Pseudomonas aeruginosa | Birth | 3.7 | Hemimeg | 22 | Vancomycin, 9 Gentamicin, 5 Cefepime, 2 Ceftriaxone, 7 Linezolid, 2 Silver Sulfadiazine, 7 |
| 7 | Lobar | Urine | Pseudomonas aeruginosa | 0.3 | 2.1 | Tuberous Sclerosis | 7 | Vancomycin, 5 Gentamicin, 4 Ciprofloxacin, 2 Ceftriaxone, 4 Ceftazidime, 5 |
| 8 | Multilobar | Urine | Pseudomonas aeruginosa | 0.1 | 1.4 | Tuberous Sclerosis | 2 | Ceftazidime, 2 Gentamicin, 2 |
| 9 | Lobar | Urine | Enterococcus species | 0.3 | 8.1 | Tuberous Sclerosis | 7 | Vancomycin, 2 Ceftriaxone, 2 |
| 10 | Hemi | Wound | CONS | 0.1 | 2.7 | Cortical Dysplasia | 5 | Vancomycin, 6 Ceftriaxone, 6 |
| 11 | Hemi | Blood | CONS | Birth | 1.0 | Cortical Dysplasia | 11 | Vancomycin, 5 Ceftazidime, 5 |
| 12 | Hemi | Resp | Staphylococcus aureus, Serratia marcescens, Candida tropicalis | 0.1 | 2.8 | Infection | 1 | Gentamicin, 12 Cotrimoxazole, 12 Rifampin, 12 Clindamycin, 3 Fluconazole, 9 Ciprofloxacin 3 |
| 13 | Hemi | Resp | respiratory syncytial virus | 1.0 | 8.8 | Infarction | 5 | Acyclovir 9 Cefdinir, 2 |
| 14 | Multilobar | Stool | Clostridium difficile | 4.0 | 6.5 | Infection | 6 | Vancomycin,7 Acyclovir, 12 Cidofovir, 3 Cefepime, 7 Metronidazole, 8 |
| 15 | Lobar | Stool | Clostridium difficile | 6.0 | 13.8 | NFI | 4 | Metronidazole, 1 |
POD = post-operative day. CONS = coagulase-negative staphylococci. Hemimeg =hemimegalencephaly. Hemi = cerebral hemispherectomy. NF1 = neurofibromatosis type 1.