Table 7.
Study number | |||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Factors | 17 | 18 | 19 | 20 | 21 | 22 | 23* | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 39 | 42 | 44 | Total | |
Individual | |||||||||||||||||||||||||
Socio-demographic | |||||||||||||||||||||||||
Education (or literacy) | ✓ | ✓ | ✓ | ✓ | ✓ | × | × | ✓ | × | × | × | ×(u) | ✓ | × | × | × | 16 | ||||||||
Age of mother | × | ✓ | × | ✓ | × | ✓ | × | × | × | × | × | ✓ | × | × | × | 15 | |||||||||
Religion | × | ✓ | ×(u) | × | 4 | ||||||||||||||||||||
Ethnicity | ✓ | 1 | |||||||||||||||||||||||
Socio-economic | |||||||||||||||||||||||||
Income activities/occupation | × | × | × | × | ✓ | × | × | × | × | 9 | |||||||||||||||
Knowledge and beliefs | |||||||||||||||||||||||||
HIV/MTCT knowledge | × | × | ✓ | ×(u) | ×(u) | × | 6 | ||||||||||||||||||
Lived in villages exposed to HIV research | ✓ | 1 | |||||||||||||||||||||||
Obstetric and pregnancy-history | |||||||||||||||||||||||||
Mother took PMTCT prophylaxis | ✓ | ✓ | 2 | ||||||||||||||||||||||
PMTCT in previous pregnancy | ✓ | 1 | |||||||||||||||||||||||
Parity | × | × | × | ✓ | ×(u) | 5 | |||||||||||||||||||
Cervical dilation | ✓ | 1 | |||||||||||||||||||||||
Term/premature delivery | ✓ | 1 | |||||||||||||||||||||||
Caesarian/vaginal delivery | × | ✓ | 2 | ||||||||||||||||||||||
Infant factors/characteristics | |||||||||||||||||||||||||
Birth weight of infant | ✓ | ✓ | 2 | ||||||||||||||||||||||
Knowledge of infant HIV status | ✓ | 1 | |||||||||||||||||||||||
At risk for neonatal death | ✓ | 1 | |||||||||||||||||||||||
Partners and community | |||||||||||||||||||||||||
Stigma | |||||||||||||||||||||||||
Internalized stigma | ✓ | ×(u) | 2 | ||||||||||||||||||||||
Experience of HIV/AIDS discrimination | ×(u) | ✓ | × | 3 | |||||||||||||||||||||
Disclosure | |||||||||||||||||||||||||
Disclosure of HIV/ARVs to partner | ✓ | ×(u) | × | ✓ | × | ✓ | ✓ | × | ×(u) | 9 | |||||||||||||||
Disclosure to anyone | × | × | ×(u) | ×(u) | ×(u) | ✓ | ✓ | 7 | |||||||||||||||||
Disclosure to other (not partner) | ✓ | 1 | |||||||||||||||||||||||
Married or living with partner | × | ✓ | ✓ | × | × | × | ×(u) | × | × | ✓ | × | 11 | |||||||||||||
Support | |||||||||||||||||||||||||
Partner VCT | × | ✓ | ×(u) | ✓ | ×(u) | × | 6 | ||||||||||||||||||
Couples VCT | × | ✓ | 2 | ||||||||||||||||||||||
Male involvement | × | ✓ | 2 | ||||||||||||||||||||||
Attendance at support group | ×(u) | ×(u) | ✓ | 3 | |||||||||||||||||||||
Health-systems | |||||||||||||||||||||||||
ARV services integrated into ANC | ✓ | × | 2 | ||||||||||||||||||||||
Client understood referral process | ✓ | 1 | |||||||||||||||||||||||
HIV status kept confidential at clinic | ✓ | 1 | |||||||||||||||||||||||
Site of PMTCT counselling | ✓ | 1 | |||||||||||||||||||||||
Place of delivery | ✓ | × | ×(u) | ✓ | ✓ | ✓ | × | ×(u) | ✓ | 9 | |||||||||||||||
Urban/rural facility | ✓ | 1 | |||||||||||||||||||||||
Number of ANC visits | ✓ | ×(u) | ✓ | × | ×(u) | ✓ | ×(u) | 7 | |||||||||||||||||
Gestational age at first ANC visit | ✓ | ×(u) | ✓ | × | ✓ | 5 | |||||||||||||||||||
HIV test after/at first ANC visit | ✓ | 1 | |||||||||||||||||||||||
Mother given NVP to take home | ✓ | 1 | |||||||||||||||||||||||
Regimen type | × | ✓ | ✓ | 3 | |||||||||||||||||||||
Universal NVP without HIV testing | ✓ | 1 |
indicates statistical evidence for an association (p<0.05 or 95% CI excludes the null value of one) was reported with at least one relevant outcome (adherence/receipt of PMTCT ARVs/cART/attendance at ART clinic).
Indicates no statistical evidence for an association
Statistical evidence for an association in uni-variate analysis only.
ANC=antenatal clinic; ARV=antiretrovirals; MTCT=mother-to-child transmission; NVP=nevirapine; PMTCT=Prevention of mother-to-child transmission; VCT=voluntary counselling and testing; ART=Antiretroviral therapy.
Study removed during sensitivity analysis of quantitative results.