Table 5.
Multivariate analysis of factors associated with 28-day and long-term survival for 510 Indigenous patients following a community-acquired BSI*
| Deaths (28 days) | Deaths (all) | 28-day survival |
Long-term survival |
||||
|---|---|---|---|---|---|---|---|
| n | HR (95% CI) | p Value | HR (95% CI) | p Value | |||
| Residence | |||||||
| Urban | 63 | 7 | 20 | 1.00 | 0.12 | 1.0 | 0.28 |
| Town camp | 125 | 20 | 37 | 1.7 (0.7 to 4.1) | 1.2 (0.7 to 2.2) | ||
| Remote | 302 | 22 | 67 | 0.9 (0.4 to 2.0) | 0.9 (0.5 to 1.5) | ||
| Age (10 years) | 1.04 (0.8 to 1.3) | 0.70 | 1.0 (0.9 to 1.1) | 0.99 | |||
| Gender (0=F,1=M) | 298F/212M | 23/26 | 65/59 | 1.5 (0.8 to 2.7) | 0.17 | 1.3 (0.9 to 2.0) | 0.13 |
| CLD (0=no, 1=yes) | 41 | 11 | 20 | 3.3 (1.6 to 6.7) | 0.001 | 2.5 (1.5 to 4.2) | <0.001 |
| Non-RHD | 37 | 9 | 16 | 2.9 (1.4 to 6.2) | 0.005 | 2.1 (1.2 to 3.6) | 0.01 |
| CRF | 28 | 6 | 11 | 2.6 (1.0 to 6.5) | 0.04 | 2.3 (1.2 to 4.3) | 0.01 |
| Malignancy | 11 | 3 | 10 | 2.9 (0.9 to 9.9) | 0.09 | 6.0 (3.0 to 12.4) | <0.001 |
| Organism† | |||||||
| Escherichia coli | 143 | 5 | 22 | 1.0 | 1.0 | ||
| Staphylococcus aureus | 83 | 7 | 18 | 2.7 (1.0 to 7.3) | 0.05 | 1.8 (1.1 to 3.0) | 0.03 |
| Klebsiella pneumoniae | 29 | 12 | 15 | 2.3 (0.7 to 7.5) | 0.17 | 1.4 (0.7 to 2.7) | 0.17 |
| Streptococcus pneumoniae | 67 | 5 | 17 | 13.4 (4.6 to 39.2) | <0.001 | 4.8 (2.5 to 9.5) | <0.001 |
| Other | 188 | 20 | 52 | 1.8 (0.5 to 6.3) | 0.37 | 1.5 (0.8 to 3.0) | 0.22 |
*Survival following the final BSI recorded during the study period. Analysis excludes 48 nosocomial BSI episodes.
†Pathogens isolated from the last positive blood cultures drawn during the study period.
BSI, bloodstream infection; CCF, congestive cardiac failure; CLD, chronic liver disease; CRF, chronic renal failure; non-RHD, non-rheumatic heart disease.