Table 2.

Brain regions showing a significant change in rCBF after anodal tDCS relative to sham tDCS

	Talairach coordinates in MNI space
Region	Side	x	y	z	Z-value
Anodal tDCS > sham tDCS
Central sulcus	L	−54	−6	52	6.08
	L	−50	−10	58	5.21
	L	−34	−12	42	5.35
Postcentral sulcus	L	−8	−38	42	5.65
	R	40	−32	46	5.39
Ventral premotor cortex	L	−40	16	24	4.89
Pre-SMA	L	−6	14	68	5.2
Caudal cingulate sulcus	R	8	−8	42	7.4
Posterior parietal cortex	R	46	−76	32	6.74
Superior frontal sulcus	R	22	52	24	4.72
Superior temporal sulcus	R	50	−42	2	5.55
Parieto-occipital sulcus	R	20	−52	18	6.37
Superior occipital gyrus	L	−8	−86	42	5.71
Fusiform gyrus	L	−30	−54	−12	7.75
Cerebellar vermis (VI)		−2	−54	−24	5.5
Thalamus (vpl)	R	16	−18	4	5.99
Sham tDCS > anodal tDCS
Superior temporal gyrus	R	68	2	2	6.81
Insular cortex	L	−28	18	6	6.75
	L	−34	−10	8	6.2
Anterior prefrontal cortex	L	−16	66	24	6.01
	R	12	70	16	5.49
Lateral prefrontal cortex	R	56	36	24	5.35
Fusiform gyrus	R	24	−46	−10	5.39
Globus pallidus	L	−10	2	−8	6.04
Nucleus accumbens	L	−12	14	−12	5.79

All co-ordinates (in standard stereotactic space) refer to maximally activated foci as indicated by the highest Z-score within a cluster of activations. x, distance (mm) to right (+) or left (−) of mid-sagital line; y, distance anterior (+) or posterior (−) to vertical plane through the anterior commissure; z, distance above (+) or below (−) the intercommissural (AC–PC) line. The AC–PC line is the horizontal line between the anterior and posterior commissures. All voxels are significant at P < 0.05 (corrected for multiple comparisons across the whole brain). R, right; L, left; SMA, supplementary motor area; vpl, ventral poster-olateral.