Table 3.

Imaging results

Region	Side	Talairach coordinates in MNI space			Z-value	Correlation analysis (r2)
		x	y	z
Primary motor cortex (BA 4a)	C	−32	−26	68	6.35	0.54
Primary motor cortex (BA 4p)	I	42	−14	44	4.72	0.68
Primary sensory cortex (BA 1)	C	−52	−14	52	5.68	0.51
Dorsolateral premotor cortex	C	−28	−8	56	6.69	0.62
	C	−52	−4	44	6.21	0.54
	C	−36	−10	64	6.02	0.56
	C	−42	−16	60	5.88	0.56
	I	32	−10	54	4.82	0.58
	I	50	−6	50	4.71	0.59
SMA	C	−6	−8	64	4.73	0.61
	I	2	−2	66	4.74	0.51
Cingulate sulcus	C	−2	−2	50	4.79	0.61
Intraparietal sulcus	C	−38	−54	58	7.28	0.57
	C	−30	−72	50	6.21	0.59
	I	26	−62	56	5.39	0.56
Dorsolateral prefrontal cortex	C	−36	36	36	4.73	0.84
	I	24	32	38	5.34	0.64

Regions in which there is a negative correlation between affected hemisphere TMS recruitment curves and task-related brain activation across all stroke patients. Images for patients with left sided lesions were flipped about the mid-sagittal line, so that all patients were assumed to have a lesion on the right side. Voxels are significant at P < 0.05, corrected for multiple comparisons across whole brain volume. Correlation analysis was performed at all significant voxels and the coefficient of determination (r²) is given. I = ipsilesional; C = contralesional; BA = Brodmann area.