Table 1.
Clinical variables of the cohort of 134 men undergoing prostate needle biopsy at two institutions in the United States.
Variable | Institution* | All | |
---|---|---|---|
Institution 1 BIDMC |
Institution 2 UM |
||
All patients | 94 (70%) | 40 (30%) | 134 (100%) |
Age (years) | 65 [60–70] | 61 [54–70] | 64 [58–70] |
Race+ | |||
Caucasian | 78 (83%) | 35 (88%) | 113 (84%) |
Non-Caucasian | 16 (17%) | 5 (12%) | 21 (16%) |
PSA (ng/mL) | 5.0 [4.0–7.0] | 5.8 [4.7–10.0] | 5.2 [4.0–8.0] |
Prostate size by TRUS (cc) | 43 [31–57] | 43 [30–56] | 43 [30–57] |
PSA density (ng/mL/cc) | 0.12 [0.08–0.19] | 0.13 [0.09–0.24] | 0.12 [0.08–0.19] |
Number of cores taken | 12 [12–12] | 12 [12–12] | 12 [12–12] |
Number of cores involved | 2 [1–4] | 10 [1–12] | 2 [1–6] |
Percent of cores involved | 17 [8–33] | 77 [8–100] | 17 [8–50] |
Prostate cancer diagnosis | |||
No | 17 (18) | 8 (20) | 25 (19) |
Yes | 77 (82) | 32 (80) | 109 (81) |
Laterality | |||
Bilateral | 23 (24) | 23 (58) | 46 (34) |
Left | 25 (27) | 2 (5) | 27 (20) |
Right | 28 (30) | 1 (3) | 29 (22) |
Unknown | 1 (1) | 6 (16) | 7 (5) |
No cancer diagnosis | 17 (18) | 8 (20) | 25 (19) |
Gleason score | |||
Gleason ≤ 6 | 27 (29) | 13 (33) | 40 (30) |
Gleason 7 | 39 (41) | 11 (28) | 50 (37) |
Gleason ≥ 8 | 8 (8) | 7 (18) | 15 (11) |
Not applicable or Unknown | 20 (21) | 9 (23) | 29 (22) |
BIDMC = Beth Israel Deaconess Medical Center; UM = University of Michigan
Abbreviations: PSA = Prostate specific antigen; TRUS = transrectal ultrasound
See Supplemental Table 1 for results on ethnicity by TMPRSS2-ERG fusion status among 100 patients’ prostate cancer-positive biopsy cores