Table 3.
Morphological features by TMPRSS2-ERG fusion status in 100 patients’ prostate cancer-positive biopsy cores
Morphological features | TMPRSS2-ERG status | ||||||
---|---|---|---|---|---|---|---|
Negative | Positive | All | |||||
N | % | N | % | N | % | P-value | |
All cores | 54 | 100 | 46 | 100 | 100 | 100 | -- |
Intraductal tumor spread | 3 | 6 | 1 | 2 | 4 | 4 | 0.62 |
Cribriform growth pattern | 4 | 7 | 11 | 24 | 15 | 15 | 0.03 |
Blue-tinged mucin | 8 | 15 | 23 | 50 | 31 | 31 | <0.01 |
Macronucleoli | 16 | 30 | 25 | 54 | 41 | 41 | 0.02 |
Foamy gland morphology | 4 | 7 | 0 | 0 | 4 | 4 | 0.12 |
Collagenous micronodules | 0 | 0 | 4 | 9 | 4 | 4 | 0.04 |
Extraprostatic extension | 1 | 2 | 0 | 0 | 1 | 1 | -- |
Perineural invasion | 6 | 11 | 9 | 20 | 15 | 15 | 0.27 |
Signet-ring cell feaures | 4 | 7 | 0 | 0 | 4 | 4 | 0.12 |
Comedonecrosis | 1 | 2 | 0 | 0 | 1 | 1 | -- |
Glomerulations | 3 | 6 | 2 | 4 | 5 | 5 | 1.0 |