Table 4.
Survey of the reversible inactivation data for the contralesional hand.
| Contralesional hand only | Motor cortical area inactivated | Control monkeys |
Anti-Nogo-A antibody treated monkeys |
|||||
|---|---|---|---|---|---|---|---|---|
| Mk-C-C-BI | Mk-C-C-CE* | Mk-C-C-RO | Mk-C-C-JU* | Mk-C-A-MO | Mk-C-A-VA | Mk-C-A-SL | ||
| Effect of muscimol infusion on horiz. slots | M1 | Yes | Yes | Yes | Yes | Yes | Yes | No |
| PMd | Yes | Yes | Yes | – | Yes | Yes | No | |
| PMv | Yes | Yes | No | – | No | Y/N | – | |
| PMv/PMd | – | – | – | Yes | – | – | – | |
| Effect of muscimol infusion on vert. slots | M1 | Yes | No | Yes | No | Yes | Yes | Yes |
| PMd | Yes | No | No | – | Yes | Yes | Yes | |
| PMv | Yes | No | No | – | No | Y/N | – | |
| PMv/PMd | – | – | – | No | – | – | – | |
| Volume M1 lesion (mm3) | 20.13 | 112.8 | 14 | 63.01 | 41.8 | 20 | 78.2 | |
| % Recovery horiz. slots | 36 | 9 | 90 | 29 | 60 | 91 | 77 | |
| % Recovery vert. slots | 94 | 59 | 100 | 46 | 84 | 87 | 77 | |
The effect of muscimol (Yes or No) after injection in M1, PMd, or PMv on the horizontal slots or on the vertical slots for the contralesional hand are based on the contact time data, reflecting here the general tendencies derived from the time points 15, 30 and 45 min post-infusion. Y/N represents divergent observations at two time points (e.g., Mk-C-A-VA). In Mk-C-C-JU, muscimol was injected at the same time in PMd and PMv.
*Two pilot monkeys taken from Ref. (32).