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. 2013 May 1;38(9):1816–1824. doi: 10.1038/npp.2013.81

Figure 2.

Figure 2

Role of CB1 receptors in social interaction. (a) AM251 (0.3–3.0 mg/kg, i.p.) decreases social interaction in saline-treated rats dose-dependently (F3,28=9.06, p<0.001). (b) AM251 (1 mg/kg, i.p.) reverses the effect of CP55,940 (0.01 mg/kg, i.p.) on phencyclidine (PCP)-induced social withdrawal (F2,42=6.80, p<0.01). Values are expressed as mean±SEM. (n=8 per group) of the time spent in social interaction(s). *p<0.05 compared with the corresponding AM251 vehicle control (VEH/V) or to saline-treated rats; #p<0.05 compared with CP55,940 vehicle controls; ¤p<0.05 compared with AM251 vehicle control.