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Cholecystokinin (CCK)2 receptors modulate AM251- and PCP-induced social withdrawal. Effects of LY225910 (LY; 0.05 mg/kg, i.p.) on PCP-, AM251- (2 mg/kg, i.p.), and URB597- (0.3 mg/kg, i.p.) induced social withdrawal (F3,56=9.78, p<0.0001). Values are expressed as mean±SEM (n=8 per group) of the time spent in social interaction(s). *p<0.05 compared with saline-treated rats; #p<0.05 compared with LY225910 vehicle (VEH) controls.
