Table 1.
Human | Mouse | Chick | Frog | Zebrafish | |
---|---|---|---|---|---|
Migration of precardiac cells from epiblast | 15-16 days | E7 | HH4 | Stage 10 | 5.5 hpf |
First evident assembly of myocardial plate | 18 days | E7 | HH5 | ∼Stage 13 | ∼13 hpf |
Generation of single heart tube initiated | 22 days | E8 | HH9 | Stage 28 | ∼19 hpf |
Tubular heart starts contraction | 23 days | E8.5 | HH10 | ∼Stage 33 | 22 hpf |
Looping | 23 days | E8.5 | HH11 | Stage 33-36 | 33 hpf |
Cushions form | 28 days | E9.5 | HH17 | ∼Stage 41 | 48 hpf |
Fishman MC, Chien KR. 1997. Fashioning the vertebrate heart: earliest embryonic decisions. Development 124(11):2099-2117.