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. Author manuscript; available in PMC: 2013 Jul 22.
Published in final edited form as: Birth Defects Res C Embryo Today. 2011 Dec;93(4):291–297. doi: 10.1002/bdrc.20219

Table 1.

Developmental age of early cardiac morphological events in different species. Adapted from Fishman and Chien (1997).

Human Mouse Chick Frog Zebrafish
Migration of precardiac cells from epiblast 15-16 days E7 HH4 Stage 10 5.5 hpf
First evident assembly of myocardial plate 18 days E7 HH5 ∼Stage 13 ∼13 hpf
Generation of single heart tube initiated 22 days E8 HH9 Stage 28 ∼19 hpf
Tubular heart starts contraction 23 days E8.5 HH10 ∼Stage 33 22 hpf
Looping 23 days E8.5 HH11 Stage 33-36 33 hpf
Cushions form 28 days E9.5 HH17 ∼Stage 41 48 hpf

Fishman MC, Chien KR. 1997. Fashioning the vertebrate heart: earliest embryonic decisions. Development 124(11):2099-2117.