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JZL184 reverses edema (Panel A) and allodynia (Panel B) when administered 3 h after carrageenan. Drug was administered immediately after the 3 h allodynia assessment. Values represent the mean (± SEM) mechanical paw withdrawal threshold and difference in paw thickness. **p<0.01 versus JZL184 at 3 h. **p<0.01, versus VEH; N = 6/group.
