Table 1. Chromosomal localization and amino acid length of all analyzed 21 env genes.
HERV-K1-6 and HERV-H1-3 numbering is according to de Parseval et al. [20]; the three envH1-3 and the six envK1-6 were each analysed with one primer pair. EnvE has a stop codon after 428 amino acids (aa) and envW2 has a stop codon after 38 amino acids or 117 bp. {ERV}= according to nomenclature of Mayer et al. [69]
| HERV {ERV}* | env | chromosome | Acc.# | coding {aa} | |
|---|---|---|---|---|---|
| 1 | F(c)2 {ERVFC1-1} | envFc2 | 7q36.2 | AC016222 | 528 |
| 2 | F(c)1 | envFc1 | Xq21.33 | AL354685 | 584 |
| 3 | FRD {ERVFRD-1} | Syncytin-2 | 6p24.1 | AL136139 | 538 |
| 4 | H1 | envH1 (p62) | 2q24.3 | AJ289709 | 585 |
| 5 | H2 | envH2 (p60) | 3q26 | AJ289710 | 563 |
| 6 | H3 | envH3 (p59) | 2q24.1 | AJ289711 | 555 |
| 7 | K1 HERV-K74261 {ERVK-21} | envK1 | 12q14.1 | AC074261.3 | 698 |
| 8 | K2 HML-2.HOM / K108 {ERVK-6} | envK2 | 7p22.1 | AC072054 | 699 |
| 9 | K3 HERV-K17833 C19 {ERVK-19} | envK3 | 19q12 | Y17833 | 694 |
| 10 | K4 HML-2 (K109) {ERVK-9} | envK4 | 6q14.1 | AF164615 | 698 |
| 11 | K5 HERV-K113 {ERVK-22} | envK5 | 19p13.11 | AY037928.1 | 699 |
| 12 | K6 HERV-K115 {ERVK-8} | envK6 | 8p23.1 | AY037929.1 | 699 |
| 13 | P(b) | Syncytin-3 | 14q32.12 | ABB52637.1 | 665 |
| 14 | R {ERV3-1} | erv-3 | 7q11.21 | AC073210 | 604 |
| 15 | R(b) {ERVPABLB-1} | envRb | 3p24.3 | AC093488 | 514 |
| 16 | T {ERVS71-1} | envT | 19p13.11 | AC078899 | 626 |
| 17 | V1 {ERVV-1} | envV1 | 19q13.41 | NM_152473 | 477 |
| 18 | V2 {ERVV-2} | envV2 | 19q13.41 | NM_001191055 | 535 |
| 19 | W {ERVW-1} | Syncytin-1 | 7q21.2 | AC000064 | 538 |
| 20 | E4-1 | envE | 19q12 | AB062274.1 | 428 |
| 21 | W2 {ERVW-2} | envW2 | Xq22.3 | FN689795 | (38) |