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. Author manuscript; available in PMC: 2013 Jul 22.
Published in final edited form as: J Immunol. 2009 Aug 26;183(6):3661–3671. doi: 10.4049/jimmunol.0901218

Figure 1. Reduced PPS-3-specific Ab responses in CD21/35−/− mice.

Figure 1

A, PPS-3-specific IgM, IgG, and IgG3 serum Ab levels in wild type (WT), CD21/35−/−, C3−/−, and C4−/− mice at 0, 7, and 14 d post i.p. immunization with PPS-3. B, Serum TNP-specific IgM, IgG, and IgG3 Ab levels in WT, CD21/35−/−, and CD19−/− mice post immunization with TNP52-Ficoll. A–B, Results were generated using 5–10 mice/genotype. Mean Ab levels (± SEM) were determined by ELISA. Significant differences between mean Ab levels are indicated by asterisks; *, p<0.05.