Table 1.

Information of excipients used in the current studies

Abbr.	Excipient name	Dosea	Functionalityb	Source
SDc	Amorphous fumed silicon dioxide	0.1 mg/ml	Glidant	Degussa Corp.; Ridgefield, NJ
CA	Citric acid	0.4 mg/ml	Acidifier	Spectrum; Gardena, CA
CCSc	Croscarmellose sodium	2.0 mg/ml	Disintegrant	FMC; Belgium
X-PVPc	Crospovidone	2.0 mg/ml	Disintegrant	ISP Technologies; Wayne, NJ
DCPc	Dicalcium phosphate dehydrate	20 mg/ml	Filler/binder	JRS Pharma; Germany
FAc	Fumaric acid	4.0 mg/ml	Acidifier	Sigma; St. Louis, MO
HPMC	Hydroxypropyl methylcellulose	20 mg/ml	Filler/binder	Dow Chemical; Midland, MI
LAC	Lactose	20 mg/ml	Filler/binder	DMV International; The Netherlands
MgStrc	Magnesium stearate	0.1 mg/ml	Lubricant	Mallincrodt; St. Louis, MO
MA	Malic acid	0.4 mg/ml	Acidifier	Spectrum; Gardena, CA
MCCc	Microcrystalline cellulose	20 mg/ml	Filler/binder	FMC; Philadelphia, PA
PEG-3350	Polyethylene glycol 3350	10 mg/ml	Plasticizer	Dow Chemical; Midland, MI
PS-80	Polysorbate-80	1.0 – 0.0001 mg/ml	Surfactant	Spectrum; Gardena, CA
PVP	Povidone	2.0 mg/ml	Filler/binder	BASF; Germany
PgSc	Pregelatinized starch	3.0 mg/ml	Filler/binder	National Starch Food; Bridgewater, NJ
PG	Propylene glycol	0.4 mg/ml	Plasticizer	Dow Chemical; Midland, MI
SLS	Sodium lauryl sulfate	2.0 mg/ml	Surfactant	Sigma; St. Louis, MO
SSGc	Sodium starch glycolate	1.0 mg/ml	Disintegrant	Mendell; Patterson, NY
SUC	Sucrose	10 mg/ml	Filler/binder	JRS Pharma; Patterson, NY

^aDose is defined as the amount of each excipient estimated to be in a tablet or capsule containing a total of 500mg of excipient dissolved in 25ml luminal volume.

^bIndividual excipient compounds are assigned to one functionality group, but may have more than one function.

^cExcipient concentration was not completely soluble in PBS.