Fig. 4.
Immunostaining for TUNEL and synaptophysin along the boundary area around the hematoma and tissue loss at 2 weeks after ICH. The number of apoptotic cells is reduced in the CP-1 treatment group compared to the control group. A higher percentage per area of cells positively reacting to synaptophysin is seen in the sections derived from CP-1-treated versus control rats. Quantitative immunoreactivities for both groups are presented as bar graphs on the right side of each panel. H&E staining showing representative sections and bar graphs of quantitative striatal tissue loss percentages in the ICH region relative to the contralateral normal region of four groups are shown in the bottom panels.