Quantitative RT-PCR for A) Hoxa5, B) Hoxa7, C) Hoxa9, D) Hoxa10, p ≤ 0.01 compared with WT thymus and E) mir-196b. Thymus from a healthy NHD13 mouse was used as a positive control and all samples were calibrated to WT thymus set to 1. CH, clinically healthy. Mice 1077, 1118, 1125 and 1138 were diagnosed with pre-T LBL. **p ≤ 0.01, ***p ≤ 0.005 by Student’s t test.