Table 1.

Mice from the X1 line with pre-T LBL.

ID	Sex	Age	Gross Findings	IHC Findings	Infiltration (H&E)	CD3	B220	FACS
1077	F	15	PE, S, T	liver	++	++	ND	thymus
				spleen	+++	+++		73% CD4+
				kidney	++	++
				lung	+++	+++
				thymus	++	+++
				bone	+	+
1118	F	13.5	H, L, S	liver	+++	+++	++	LN
				spleen	+++	+++	+	68% CD3+B220+
				kidney	+	+	−
				lung	++	++	+
				LN	+++	++	++
				bone	++	++	+
1138	M	10	H, L, S, K	liver	+++	faint staining	ND	spleen
				spleen	+++	across		58% CD4+8+
				kidney	++	all
				lung	++	tissues
				bone	+++	examined
1125	F	15	T	liver	−	−	ND	thymus
				spleen	−	++		61% CD8+
				kidney	−	−
				lung	++	++
				thymus	+++	+++
				bone	+	+

H, hepatomegaly; K, enlarged/pale kidneys; L, lymphadenopathy; PE, pleural effusion; S, splenomegaly; T, thymoma, ND, not determined