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. Author manuscript; available in PMC: 2013 Jul 22.
Published in final edited form as: Glycoconj J. 2012 May 26;30(1):33–40. doi: 10.1007/s10719-012-9390-5

Table 1.

Known zebrafish glycosylation mutants

Glycan Type/Modification Mutant Name Gene Primary Phenotypes
Fucosylation slytherin (srn) gmds Defects in neurogenesis, gliogenesis, axonal pathfinding, and synapse formation [ref 65, 66]
towhead (twd) gmds Altered migration of vagus motor neuron progenitors [ref 71]
GAG biosynthesis dackel (dak) ext2 Altered cartilage development, reduced osteoblast differentiation, optic tract missorting [ref 93, 94]
boxer (box) extl3 Optic tract missorting [93]
xylt1 xylt1 Altered craniofacial chondrogenesis and accelerated osteogenesis [ref 92]
Nucleotide-sugar biosynthesis jekell (jek) udgh Defects in craniofacial and cardiac valve formation [ref 91]
perplexed (per) cad Abnormal craniofacial formation [ref 82]
man 'o war (mow) uxs1 Defects in craniofacial and cardiac valve formation, decreased osteogenesis [ref 90]
GAG modifying enzymes fam20b fam20b Altered chondrogenesis and accelerated osteogenesis [ref 92]
pinscher (pic) papst1 Altered chondrogenesis and osteogenesis [ref 94]