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. Author manuscript; available in PMC: 2013 Jul 22.
Published in final edited form as: Nat Immunol. 2012 Aug 26;13(10):947–953. doi: 10.1038/ni.2403

Figure 7. IL22 Restores SFB homeostasis and perigonadal fat pad expansion in LTβR−/− mice.

Figure 7

LTβR−/− females were treated with 10 µg of plasmid encoding empty vector (p-Erk), IL-22, IL-23-Ig, or IL-17A at the start of diet. (a) RT-PCR for SFB normalized to Day 0 of diet are plotted. (b–c) (B) total body weight and (c) perigonadal fat pads were weighed and are plotted as a percentage of final weight. (n=5–10 mice per group; Student’s t-test for log-transformed data for SFB; Two-tailed Mann-Whitney test for body weight and perigonadal fat due to outlier in p-ERK group; * P <0.05, ** P <0.01)