Table 4.

Proportion of at least 90% adherence by intervention type by per-protocol analysis.

	Time (weeks)
	1–12	13–24	25–36	37–48	1–48
Summary groups
Control	0.62	0.55	0.54	0.54	0.47
N	133	128	124	119	119
Daily (all)	0.64 (0.80)	0.61 (0.40)	0.52 (0.76)	0.56 (0.78)	0.50 (0.70)
Weekly (all)	0.68 (0.35)	0.65 (0.10)	0.62 (0.19)	0.64 (0.1)	0.63 (0.01)*
Short (all)	0.65 (0.64)	0.62 (0.28)	0.58 (0.50)	0.62 (0.19)	0.59 (0.07)
Long (all)	0.67 (0.46)	0.64 (0.16)	0.56 (0.72)	0.58 (0.51)	0.55 (0.23)
Subgroups
Daily, short	0.59 (0.65)	0.58 (0.74)	0.57 (0.74)	0.56 (0.77)	0.49 (0.80)
N	66	62	60	57	57
Weekly, short	0.71 (0.22)	0.66 (0.16)	0.60 (0.45)	0.68 (0.07)	0.68 (0.01)*
N	66	62	60	57	57
Daily, long	0.69 (0.38)	0.63 (0.31)	0.48 (0.41)	0.55 (0.88)	0.50 (0.71)
N	67	65	61	60	60
Weekly, long	0.65 (0.74)	0.65 (0.21)	0.64 (0.18)	0.61 (0.37)	0.59 (0.12)
N	71	68	67	66	66
Any treatment	0.66 (0.49)	0.63 (0.15)	0.57 (0.55)	0.6 (0.26)	0.57 (0.09)
N	270	257	248	240	240

P-value from comparison of each intervention group with control group is indicated in parentheses.

^*P < 0.05.