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. Author manuscript; available in PMC: 2013 Jul 22.
Published in final edited form as: Chem Commun (Camb). 2011 Feb 8;47(14):4074–4080. doi: 10.1039/c0cc02960b

Figure 8.

Figure 8

Cyclization-rearrangement of syn-CPP to syn-aphidicolene catalyzed by syn-pimaradiene synthase upon substitution of a particular Thr with Ile.52