TABLE 4.
Correlations of echocardiographic parameters and natriuretic peptides with pulmonary capillary wedge pressure (PCWP) in patients after orthotopic heart transplantation having normal PCWP at rest (n=50) and in all exercised patients (n=61; values in parentheses)
|
Correlation coefficients
|
||
|---|---|---|
| Values at rest in horizontal position | Peak exercise values‡ | |
| Natriuretic peptides | ||
| Pro-ANP, nmol/L | 0.31 (0.33*) | 0.30 (0.27)‡ |
| BNP, pmol/L | 0.23 (0.18) | 0.10 (0.15)‡ |
| Pulsed-wave Doppler | ||
| E, cm/s | 0.22 (0.44†) | 0.35* (0.45†) |
| DT, ms | −0.22 (−0.38†) | −0.53† (−0.50†) |
| Doppler tissue imaging and derived indexes | ||
| e′, cm/s | −0.17 (−0.18) | −0.17 (−0.19) |
| s′, cm/s | −0.41† (−0.44†) | −0.22 (−0.22) |
| E/e′ | 0.29* (0.48†) | 0.36* (0.42†) |
| E/s′ | 0.39† (0.59†) | 0.40† (0.46†) |
| Two-dimensional speckle-tracking echocardiography and derived indexes | ||
| SR-E, 1/s | 0.15 (0.03) | −0.15 (−0.26) |
| SR-S, 1/s | 0.08 (0.13) | 0.51† (0.48†) |
| E/SR-E, cm | 0.01 (0.19) | 0.25 (0.44†) |
| E/SR-S, cm | −0.39* (−0.44†) | −0.59† (−0.63†) |
*
P<0.05;
†
P<0.01;
‡
Postexercise values. BNP Brain natriuretic peptide; DT Deceleration time of E wave; E Peak early diastolic transmitral velocity; e′ Peak early diastolic mitral annular velocity; Pro-ANP Pro-atrial natriuretic peptide; s′ Peak systolic mitral annular velocity; SR-E Strain rate at early diastole; SR-S Systolic strain rate