Figure 2).

Effects of in vitro ischemia/reperfusion (I/R) on mitochondrial respiration (left panel) and respiratory control ratio (RCR) (right panel) using the substrates pyruvate/malate, succinate only, succinate/rotenone and adenosine diphosphate. In vitro I/R significantly decreased oxygen consumption rate and RCR when pyruvate/malate or succinate/rotenone were used as substrates. When succinate was used in the absence of rotenone, in vitro I/R significantly increased mitochondrial respiration and RCR. Data are presented as mean ± SD; n=8/group. Con Control