TABLE 1.

Cardiac structure and function

Group	LVEDD, mm	LVPWEDT, mm	HW/BW, mg/g	IS	Heart rate, beats/min	LVEF
0 weeks
MI+HCQ (n=10)	5.61±0.61	1.24±0.06	–	–	447.34±35.61	0.67±0.06
MI (n=9)	5.60±0.62	1.24±0.06	–	–	448.14±34.75	0.68±0.06
Sham+HCQ (n=7)	5.59±0.60	1.22±0.07	–	–	439.25±36.35	0.69±0.07
Sham (n=7)	5.58±0.59	1.22±0.06	–	–	438.43±35.26	0.70±0.08
12 weeks
MI+HCQ (n=10)	6.36±0.62*	1.50±0.09*‡	2.62±0.18*†‡	0.33±0.04†‡	435.37±35.24	0.62±0.06*†‡
MI (n=9)	7.20±0.63†‡	1.25±0.08†‡	2.88±0.19†‡	0.32±0.03†‡	452.87±36.32†‡	0.48±0.05†‡
Sham+HCQ (n=7)	5.96±0.61	1.52±0.10‡	2.31±0.17	0	411.23±35.61	0.70±0.07
Sham (n=7)	5.74±0.62	1.37±0.09	2.23±0.16	0	410.27±36.27	0.71±0.06

Data presented as mean ± SD.

^*P<0.05 compared with myocardial infarction (MI) group;

^†P<0.05 compared with sham + hydroxychloroquine (HCQ) group;

^‡P<0.05 compared with sham operation (Sham) group. BW Body weight; HR Heart rate; HW Heart weight; IS Infarction size; LVEDD Left ventricular end-diastolic diameter; LVEF LV ejection fraction; LVPWEDT LV posterior wall end-diastolic thickness