TABLE 2.
Left ventricular function parameters measured during catheterization
| Parameters | Control | Three weeks AB | Three weeks AB; one week DB | Four weeks AB | Four weeks AB; one week DB | Six weeks AB | Six weeks AB; one week DB | Six weeks AB; two weeks DB |
|---|---|---|---|---|---|---|---|---|
| n | 10 | 10 | 10 | 10 | 9 | 8 | 6 | 6 |
| LVPs, mmHg | 84.2±2.7 | 179.4±5.3* | 115.3±4.9*† | 162.1±5.4* | 114.4±10.0*† | 126.2±7.8* | 93.9±10.5† | 82.2±1.5 |
| LVPdev, mmHg | 82.2±2.8 | 178.3±19.4* | 116.6±4.4*† | 156.2±6.3* | 107.3±9.2*† | 111.4±10.1 | 76.5±7.8 | 76.4±2.8 |
| LVEDP, mmHg | 9.6±1.9 | 8.5±2.0 | 5.2±0.5 | 16.1±2.8* | 10.5±2.2 | 20.8±1.3* | 23.2±3.2* | 19.1±1.8* |
| +dp/dt, +mmHg/s | 3777±201 | 5911±237* | 7452±993*† | 4396±427 | 3397±159 | 3243±240* | 3131±199* | 3332±218 |
| −dp/dt, −mmHg/s | 4389±259 | 8395±277* | 7748±516* | 6071±580 | 4253±246 | 3207±540* | 2874±574* | 3306±279* |
| HR, beats/min | 375±41 | 407±30 | 393±26 | 372±29 | 394±28 | 361±41 | 382±41 | 390±21 |
Data presented as mean ± SEM unless otherwise indicated.
*
P<0.05 compared with control group;
†
P<0.05 compared with related aortic banding (AB) group. +dp/dt Rate of pressure rise; −dp/dt Rate of pressure fall; DB Aortic debanding; HR Heart rate; LVEDP Left ventricular end-diastolic pressure; LVPdev Left ventricular developed pressure; LVPs Left ventricular systolic pressure