Table 1.
Univariate analysis of clinical variables of 142 patient visits with hyperglycemic crises precipitated by infection
| Variable | Survival (n = 115) | 30-day mortality (n = 27) | P-value | All (n = 142) |
|---|---|---|---|---|
| Age, mean ± SD |
67.5 ± 17.1 |
72.4 ± 19.7 |
0.200 |
68.4 ± 17.6 |
| Elderly (≥ 65 years old), % |
62.6 |
81.5 |
0.073 |
66.2 |
| Gender: Male, % |
37.4 |
48.1 |
0.303 |
39.4 |
| Altered mental status, % |
53.0 |
77.8 |
0.029 |
57.7 |
| SBP, mean ± SD |
135.0 ± 32.0 |
127.5 ± 36.7 |
0.289 |
133.6 ± 32.9 |
| Heart rate, mean ± SD |
118.1 ± 21.3 |
106.0 ± 26.3 |
0.013 |
115.8 ± 22.8 |
| Body temperature, mean ± SD |
37.3 ± 1.2 |
37.1 ± 1.4 |
0.387 |
37.2 ± 1.2 |
| Respiratory rate, mean ± SD |
22.1 ± 6.1 |
21.9 ± 6.5 |
0.898 |
22.1 ± 6.1 |
| Medical history, % |
|
|
|
|
| Hypertension |
53.9 |
48.1 |
0.589 |
52.8 |
| Diabetes |
82.6 |
88.9 |
0.567 |
83.8 |
| Stroke |
33.0 |
33.3 |
>0.95 |
33.1 |
| Chronic renal insufficiency |
14.8 |
25.9 |
0.166 |
16.9 |
| Cancer |
7.8 |
29.6 |
0.005 |
12.0 |
| Bedridden |
20.0 |
25.9 |
0.600 |
21.1 |
| Infection source, %* |
|
|
|
|
| Low respiratory tract |
31.3 |
25.9 |
0.649 |
30.3 |
| Urinary tract |
52.2 |
37.0 |
0.157 |
49.3 |
| Skin or soft tissue |
10.4 |
18.5 |
0.319 |
12.0 |
| Intra-abdominal |
5.2 |
11.1 |
0.372 |
6.3 |
| Meningitis |
0.9 |
0.0 |
>0.95 |
0.7 |
| Bone/joint |
0.9 |
0.0 |
>0.95 |
0.7 |
| Perianal abscess |
0.0 |
3.7 |
0.190 |
0.7 |
| Psoas muscle abscess |
0.9 |
0.0 |
>0.95 |
0.7 |
| Sepsis without focus |
0.9 |
0.0 |
>0.95 |
0.7 |
| Subgroup diagnosis, % |
|
|
|
|
| DKA |
22.6 |
14.8 |
0.443 |
21.1 |
| HHS |
64.3 |
66.7 |
>0.95 |
64.8 |
| Mixed DKA/HHS | 13.0 | 18.5 | 0.538 | 14.1 |
SD standard deviation, SBP systolic blood pressure, DKA diabetic ketoacidosis, HHS hyperosmolar hyperglycemic state.
*Patient may have multiple infection sources.