Table 1.
NCBI accession numbers (number.version) of GDP-L-fucose synthesis-associated genes referenced in this study
| Source organism | Gene identifier a | Nt accession | Prot. accession | Function b | References |
|---|---|---|---|---|---|
|
Homo sapiens |
GMDS |
NM_001500.2 |
NP_001491.1 |
GMD |
[36-39] |
| |
TSTA3/FX |
NM_003313.3 |
NP_003304.1 |
GMER |
[20,37,40,41] |
| |
FUK |
NM_145059.2 |
NP_659496.2 |
FUK |
[14] |
| |
FPGT/GFPP |
NM_003838.3 |
NP_003829.2 |
FPGT |
[13,42,43] |
|
Mus musculus |
Gmds |
NM_146041.2 |
NP_666153.1 |
GMD |
[22] |
| |
Tsta3 |
NM_031201.1 |
NP_112478.1 |
GMER |
[22,44,45] |
| |
Fuk |
NM_172283.2 |
NP_758487.2 |
FUK |
[15] |
| |
Fpgt |
NM_029330.2 |
NP_083606.2 |
FPGT |
" " |
|
Danio rerio |
gmds |
NM_200489.2 |
NP_956783.2 |
GMD |
[46,47] |
|
Drosophila melanogaster |
Gmd |
NM_135044.3 |
NP_608888.2 |
GMD |
[11,18] |
| |
Gmer |
NM_137890.2 |
NP_611734.1 |
GMER |
" " |
|
Caenorhabditis elegans |
gmd-1 |
AM231683.1 |
CAJ77752.1 |
GMD |
[11] |
| |
gmd-2 |
NM_060705.1 |
NP_493106.1 |
" " |
" " |
| |
ger-1 |
NM_066139.3 |
NP_498540.1 |
GMER |
" " |
|
Schistosoma mansoni |
GMD |
GU574757.1 |
ADO17520.1 |
GMD |
Present study |
| |
GMER |
GU574758.1 |
ADO17521.1 |
GMER |
" " |
|
Mortierella alpina |
GMD |
GU299800.1 |
ADC54120.1 |
GMD |
[48] |
| |
GMER |
GU299801.1 |
ADC54121.1 |
GMER |
" " |
|
Arabidopsis thaliana |
GMD1 |
NM_126026.3 |
NP_201429.1 |
GMD |
[11,49] |
| |
MUR1/GMD2 |
NM_114976.3 |
NP_190685.2 |
" " |
[11,49,50] |
| |
GER1 |
NM_105984.3 |
NP_177468.2 |
GMER |
[11,51,52] |
| |
GER2 |
NM_101652.2 |
NP_564040.1 |
" " |
[11] |
| |
FKGP |
NM_100004.3 |
NP_563620.1 |
FUK/FPGT (dual) |
[17] |
|
Bacteroides fragilis |
Gmd |
CR626927.1 |
CAH07586.1 |
GMD |
[16] |
| |
Fcl |
CR626927.1 |
CAH07585.1 |
GMER |
" " |
| Fkp | NC_003228.3 | YP_212230.1 | FUK/FPGT (dual) | [16,53] |
a Official gene names/identifiers are provided. Genes in boldface type were used as query sequences to search for homologs in the SchistoDB [35].
b GMD, GDP-D-mannose-4,6-dehydratase; GMER, GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; FUK, L-fucose kinase; FPGT, fucose-1-phosphate guanylyltransferase; FUK/FPGT, bifunctional L-fucose kinase/fucose-1-phosphate guanylyltransferase.